Extracellular Vesicle‐Educated Macrophages Promote Early Achilles Tendon Healing
Tendon healing follows a complex series of coordinated events, which ultimately produces a mechanically inferior tissue more scar‐like than native tendon. More regenerative healing occurs when anti‐inflammatory M2 macrophages play a more dominant role.
Human blood vessel organoids as a model of diabetic vasculopathy
The increasing prevalence of diabetes has resulted in a global epidemic1. Diabetes is a major cause of blindness, kidney failure, heart attacks, stroke and amputation of lower limbs.
Fourth baby born after uterus transplant in Dallas
Kayla and Lance Edwards are excited to publicly announce the birth of their daughter Indy Pearl Edwards through a landmark uterus transplant clinical trial at Baylor University Medical Center at Dallas, a part of Baylor Scott & White Health.
Team uses organoid technology and single-cell RNA sequencing to study bladder cancer
Investigation of biological mechanisms in urothelial tissue, one of the three types of tissue that make up the urinary system, has always been very limited due to the lack of technologies that allow working with stable and long-term populations of the cells that compose it.
Possible Therapeutic Target For Slow Healing Of Aged Muscles Discovered
An age-related decline in recovery from muscle injury can be traced to a protein that suppresses the special ability of muscle stem cells to build new muscles, according to work from a team of current and former Carnegie biologists led by Chen-Ming Fan and published in Nature Metabolism.
Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin
Dermal papilla cells (DPCs) play a pivotal role in the regulation of hair follicle (HF) growth, formation, and cycling, mainly through paracrine mechanisms. In the last decade, extracellular vesicles (EVs) have been recognized as a new paracrine mechanism that can modify the physiological state of recipient cells by transferring biological material.
New insights into the healing capacity of the heart
A group of researchers at Baylor College of Medicine, the Texas Heart Institute and the University of Texas Health Science Center at Houston reveals today in the journal Genes & Development new insights into the recently discovered healing capacity of the heart involving the Hippo cellular pathway.
Long-Term Study Shows Endothelial Progenitor Cells Are Safe for Treating Stroke Patients
A new study recently published in STEM CELLS Translational Medicine demonstrates the long-term safety of laboratory-expanded endothelial progenitor cells for treating ischemic stroke
Kidney-Resident Macrophages — a role for Healing During Acute Kidney Injury
During development in the womb, immune cells called macrophages go to the kidneys and remain there for life. Understanding the possible healing role for these macrophages after kidney damage may be crucial to helping treat patients who suffer acute kidney injury.
Core-Shell Nanofibrous Scaffolds for Repair of Meniscus Tears
Electrospinning is an attractive method of fabricating nanofibers that replicate the ultrastructure of the human meniscus. However, it is challenging to approximate the mechanical properties of meniscal tissue while maintaining the biocompatibility of collagen fibers.