How signalling proteins affect wound healing
What do a scraped knee, a paper cut, or any form of surgery have in common? The short answer is a wound in need of healing—but the long answer lies in a series of biological activities that allow tissues to repair themselves.
Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma
Preclinical studies suggest that bb2121, a chimeric antigen receptor (CAR) T-cell therapy that targets B-cell maturation antigen (BCMA), has potential for the treatment of multiple myeloma.
Gene therapy durably reverses congenital deafness in mice
In collaboration with the universities of Miami, Columbia and San Francisco, scientists from the Institut Pasteur, Inserm, CNRS, Collège de France, Sorbonne University and the University of Clermont Auvergne have restored hearing in an adult mouse model of DFNB9 deafness—a hearing disorder that represents one of the most frequent cases of congenital genetic deafness.
Scientists generate high-quality human vascular cells through genome editing technology
Scientists from the Institute of Biophysics of the Chinese Academy of Sciences (CAS), Peking University and the Institute of Zoology of CAS have generated the worlds first genetically enhanced human vascular cells by targeting a single longevity gene, FOXO3. The study was recently published in Cell Stem Cell.
Sacrificial ink-writing technique allows 3D printing of large, vascularized human organ building blocks
20 people die every day waiting for an organ transplant in the United States, and while more than 30,000 transplants are now performed annually, there are over 113,000 patients currently on organ waitlists.
High-tech gel aids delivery of drugs
Drugs that help prevent the formation of unwanted or harmful proteins are currently being developed to treat a number of diseases, including cancer.
Accidental Discovery of New T-Cell Hailed as Major Breakthrough for ‘Universal’ Cancer Therapy
Researchers at Cardiff University have discovered a new type of killer T-cell that offers hope of a “one-size-fits-all” cancer therapy.
Scientists discover bodys protection shield
Scientists have discovered a way to manipulate the body’s own immune response to help boost tissue repair. The findings, published in Current Biology today [Monday 18 November], reveal a new network of protective factors to shield cells against damage.
New cell therapy improves memory and stops seizures following TBI
Researchers from the University of California, Irvine developed a breakthrough cell therapy to improve memory and prevent seizures in mice following traumatic brain injury. The study, titled "Transplanted interneurons improve memory precision after traumatic brain injury," was published today in Nature Communications.
Living skin can now be 3D-printed with blood vessels included
Researchers at Rensselaer Polytechnic Institute have developed a way to 3D print living skin, complete with blood vessels. The advancement, published online today in Tissue Engineering Part A, is a significant step toward creating grafts that are more like the skin our bodies produce naturally.
