Regenerative Medicine and Stem Cells Technologies

Recent research from the laboratory of Alexandra J. Harvey (University of Melbourne, Victoria, Australia) established that induced pluripotent stem cells (iPSCs) fail to modulate carbohydrate and amino acid utilization in response to oxygen [1] when compared to embryonic stem cells (ESCs) or preimplantation embryos.

A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer’s and Parkinson’s diseases and other neurological disorders.

Research conducted aboard the International Space Station will look at how nerve cells interact with key immune cells of the brain in low-gravity conditions. The goal is to better understand nervous system damage in Parkinson’s disease and multiple sclerosis (MS) — and help improve their treatments.

When it comes to heart disease, the health of the scaffold where cardiac cells grow may be a much bigger factor than previously believed.

A new immunodeficiency disease caused by a novel genetic mutation has been identified by researchers at the University of Colorado Anschutz Medical Campus providing unique insights into cell biology.

A recent study published in Nature Chemical Biology has found a method its authors say improves on the Nobel prize-winning cellular reprogramming method developed by Shinya Yamanaka, M.D., Ph.D. — making it possible to produce cells in a considerably shorter time and with greater success.

Age-related macular degeneration (AMD) is one of the most common causes of vision loss in people over age 65. The exact cause is unknown, but the fact that a family history of AMD increases a persons risk for the condition suggests genetics play an important role.

Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed bone repair.

Stem cell‐derived exosomes have exhibited promise for applications in tissue regeneration. However, one major problem for stem cell‐derived exosome therapies is identifying appropriate source cells.

Scientists have created miniature brains from stem cells that developed functional neural networks. Despite being a million times smaller than human brains, these lab-grown brains are the first observed to produce brain waves that resemble those of preterm babies. The study, published August 29 in the journal Cell Stem Cell, could help scientists better understand human brain development.