Regenerative Medicine and Stem Cells Technologies

Cells made by fusing a normal human muscle cell with a muscle cell from a person with Duchenne muscular dystrophy —a rare but fatal form of muscular dystrophy—were able to significantly improve muscle function when implanted into the muscles of a mouse model of the disease. The findings are reported by researchers from the University of Illinois at Chicago in the Stem Cell Review and Reports.

A team of researchers at UC Davis has succeeded in growing capillaries on and into a neural organoid. In their paper published in the journal NeuroReport, the group describes how they grew capillaries with the organoid and their hopes that such research will one day lead to therapies for treating brain damage in people.

Relapsed/refractory mantle cell lymphoma (MCL) is an aggressive disease that could benefit from the addition of chimeric antigen receptor (CAR) T-cell therapy. The ongoing ZUMA-2 trial is investigating the use of the anti-CD19 CAR T-cell product axicabtagene ciloleucel (axi-cel; Yescarta) in patients with relapsed/refractory MCL (NCT02601313).

Acyclic retinoid, an artificial compound derived from vitamin A, has been found to prevent the recurrence of hepatocellular carcinoma (HCC), the most common form of liver cancer. Now, in research published in Proceedings of the National Academy of Sciences, scientists have discovered that the compound targets one class of cancer stem cells, preventing them from giving rise to new tumors.

Scientists at have developed a breakthrough CRISPR gene-editing tool, that could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code.

In Ridley Scotts seminal blockbuster Blade Runner, humanity has harnessed bio-engineering to create a race of replicants that look, act and sound human - but are made entirely from synthetic material.

Market Research Report on “Global CAR T Cell Therapy Market-Industry Analysis, Size, Share, Growth, Trends and Forecast, 2017-2025” is provided by Orbis Research. Get Custom Research on Requirement.

Carl H. June, MD, has been named to Time magazine’s 100 most influential people in the world for 2018.

Natural killer cells are a form of granular lymphocytes of varying sizes that play an important role in innate immunity in the human body. They typically constitute of around 10% of total blood lymphocytes as compared to around 70% and 20% of T cells and B cells, respectively.

Lobbyists representing cancer hospitals are urging Medicare officials to create a new set of payments for new, expensive CAR-T treatments.