Regenerative Medicine and Stem Cells Technologies

Now, in research published in Cell Reports, a team from the RIKEN Preventive Medicine and Diagnosis Innovation Program (PMI) and other institutes has some potentially comforting news.

The Food and Drug Administration approved a second version of a groundbreaking treatment Wednesday that genetically alters patients’ cells to attack cancer – this time, to fight aggressive non-Hodgkin lymphoma.

Researchers from the University of Nebraska-Lincoln, Harvard Medical School and MIT have designed a smart bandage that could eventually heal chronic wounds or battlefield injuries with every fiber of its being.

Human cancer genomes harbor cryptic mutational signatures that represent the cumulative effects of DNA damage and defects in DNA repair processes. Knowledge of how specific signatures originate could have a major impact on cancer diagnosis and prevention

Researchers from the Wellcome Trust Sanger Institute in the U.K. and their collaborators have developed what could potentially be a tabula rasa, or clean slate, for stem cells, which could allow any type of cells to grow and develop. This breakthrough study is published today in the journal Nature, and it shows how researchers, for the first time, created what’s known as Expanded Potential Stem Cells (EPSCs) in mice.

Patients with short bowel syndrome lack sufficient functional intestine to sustain themselves with enteral intake alone. Transplantable vascularized bioengineered intestine could restore nutrient absorption.

Genetic screens have revolutionized our understanding of biological processes and disease mechanisms. Recent technical advances have broadened the available approaches for disrupting gene function in a cell population prior to screening, from chemical and insertional mutagenesis to RNA interference, and, most recently, CRISPR-mediated genome editing.

The efficacy of conventional anti-tumor immunotherapeutic approaches is markedly affected by the immunosuppressive microenvironment of tumor. Since adenosine is one of the main orchestra leaders in immunosuppression symphony of tumor, targeting its producing molecules such as CD73 can help to achieve a better clinical outcome following conventional cancer immunotherapeutic approaches

Polycystic kidney disease affects 12 million people. Until recently, scientists have been unable to recreate the progression of this human disease in a laboratory setting.

When you were a child you might have a carefree attitude towards your health and life. Over time, with increasing age suddenly a patch of fine lines on your face may attract your attention and starts troubling you