Regenerative Medicine and Stem Cells Technologies

Fate Therapeutics a clinical-stage biopharmaceutical company dedicated to the development of programmed cellular immunotherapies for cancer and immune disorders, announced today that the Company is presenting new preclinical data on FT819, its off-the-shelf CAR T-cell product candidate, at the American Association for Cancer Research (AACR) Annual Meeting being held from April 14-18, 2018 in Chicago, Illinois.

The heart is the first organ to develop in the womb and the first cause of concern for many parents.

Autologous stem cell transplantation (auto-HSCT) is an effective treatment strategy for hematological malignancies. The standard mode of handling hematopoietic progenitors for the autologous procedure (CRYO) consists on its collection and freezing with dimethyl sulfoxide (DMSO) and its subsequent thawing and re-infusion.

The immune cells known as macrophages have a long to-do list in our bodies. They defend us from bacteria, coax wounds to heal, and perform other vital tasks. A surprising new study suggests they are also essential for the heart to beat normally. That could make macrophages prime targets for treating conditions like arrhythmias, in which the heart beats erratically.

The ability to rewrite the genetic code for life is a powerful one. In the past few years, scientists have revolutionized our ability to do so with the discovery and refinement of a molecular tool called CRISPR that allows us to edit sections of DNA. This tool can snip specific parts of genetic code out and replace them with new segments, eliminating diseases or giving creatures whole new traits.

Swiss drugmaker Novartis said Monday that it will acquire a Chicago-based gene therapy company that has been working on a new treatment for infants in an $8.7 billion deal.

Pfizer and Allogene Therapeutics have entered into a contribution agreement for Pfizer’s portfolio of assets related to donor-derived chimeric antigen receptor T-cell (CAR T) therapy, a kind of cell therapy directed at blood cancers and solid tumors.

Freezing and subsequent transfer of embryos gives infertile couples just as much of a chance of having a child as using fresh embryos for in vitro fertilization (IVF), research from Ho Chi Minh City, Vietnam, and Adelaide, Australia has found.

2.5 billion. Thats approximately the number of times the human heart beats in 70 years. And sometimes during the course of its unrelenting contractions and relaxations, the heart muscle can no longer bear the strain.

Adult male mice lacking a gene linked to intellectual disability have trouble completing and remembering mazes, with no changes in social or repetitive behavior, according to new research published in JNeurosci. This animal model provides a new way to study the role of this gene in learning and memory and provides a rodent model of pure intellectual disability.