Regenerative Medicine and Stem Cells Technologies

In the Cellular Immunotherapy and Transplantation Program at Virginia Commonwealth University Massey Cancer Center, scientists are pursuing a cross-collaborative effort that could potentially change the way cellular immunotherapies such as stem cell transplantation and CAR T-cell therapies are performed.

It comes after a British man, who has not been named, was declared in remission of the Aids virus earlier this week - making him only the second in the world.

Cancer: The word alone evokes dread, anxiety, and fear. Accordingly, many women living with the disease and undergoing treatment experience chronic stress and depression. Scientists have demonstrated, in studies with rodents and humans, that stress can exacerbate cancers progression, but it wasnt clear how.

A team of Tufts University-led researchers has developed three-dimensional (3-D) human tissue culture models for the central nervous system that mimic structural and functional features of the brain and demonstrate neural activity sustained over a period of many months.

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.

A London man appears to be free of HIV after a stem cell transplant, the second success including the "Berlin patient", doctors reported.

Researchers from The University of Texas Medical Branch at Galveston have developed a promising drug that has proven to significantly increase muscle size, strength and metabolic state in aged mice, according to a study just published in Biochemical Pharmacology.

Investigators at Childrens Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the door for future interventions in retinoblastoma (RB), a tumor of the retina that affects children under five years of age.

Mammalian embryos are unlike those of any other organism as they must grow within the mothers body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such as head, tail or vital organ

The neurodegenerative disease ALS causes motor neuron death and paralysis. However, long before the cells die, they lose contact with muscles as their axons atrophy. Researchers at Karolinska Institutet in Sweden have now devised a method that radically improves the ability to study axons and thus to better understand the pathological development of ALS. The method is described in the scientific journal Stem Cell Reports.