Regenerative Medicine and Stem Cells Technologies

Tissues rely on stem cells (SCs) for homeostasis and wound repair. SCs reside in specialized microenvironments (niches) whose complexities and roles in orchestrating tissue growth are still unfolding. Here, we identify lymphatic capillaries as critical SC-niche components.

Cellular soldiers created using the bodys own defenses can track down and kill escaping cancer cells during surgeries, preventing metastasis and saving lives, a Vanderbilt University biomedical engineer has discovered, particularly in cases of triple negative breast cancer.

Preeclampsia is the leading cause of death and disability, for both mothers and babies, killing approximately 76,000 mothers and 500,000 babies globally every year. Despite this, the only cure at present is to deliver the placenta and the baby, with the potential for long term complications.

Diabetes, cardiovascular disease, Parkinsons and Alzheimers disease make up the worlds most common diseases. A new biobank at Lund University in Sweden—the largest of its kind—with stem cells from both those affected and healthy individuals, will contribute to an increased understanding of how these diseases arise.

Researchers at Columbia University were able to grow fully functional lungs in mouse embryos using transplanted stem cells.

Researchers have lifted fertility rates in older female mice with small doses of a metabolic compound that reverses the aging process in eggs, offering hope for some women struggling to conceive.

Specifically programmed materials can, under specific conditions, encourage stem cells to transform into bone cells—as revealed by a German research team under the leadership of the Helmholtz-Zentrum Geesthacht, Centre for Materials and Coastal Research.

Proteasome inhibitors, immunomodulatory agents and monoclonal antibodies have dramatically changed the natural history of multiple myeloma (MM).

For more than a decade, researchers have been working to create artificial digital retinas that can be implanted in the eye to allow the blind to see again.

Scientists suggest a new strategy that uses induced pluripotent stem cells (iPSCs) to regulate immune reaction to transplanted tissues.