Regenerative Medicine and Stem Cells Technologies

Conventional thinking is that bone regeneration is left to a small number of mighty cells called skeletal stem cells, which reside within larger groups of bone marrow stromal cells.

Using Induced pluripotent stem cells (iPSCs), researchers have for the first time profiled the complete genetic programs of early lung progenitors identifying genes that control lung formation and have created mini-lung organoids (artificially grown cells that resemble those of an organ) that can be used to model human lungs.

The outbreak of corona has led to the cooperation of domestic and international researchers to defeat the disease with the help of science and technology. Meanwhile, stem cells and regenerative medicine is one of the fields that has a great capacity for the production of vaccines and stem cell-based products to fight the disease.

Thousands of Americans suffer from the delay or non-appearance of puberty. While the underlying cause is failure in the correct action of the hypothalamic hormone GnRH, the precise genetic causes have not been fully understood.

Researchers have discovered ways to boost CAR T-cell therapy. According to a study published in the Blood journal, drug profiling and the CRISPR-Cas9 gene editing method have opened new avenues in the development of CAR T-cell therapy, used to treat leukemia and lymphoma.

Researchers at the University of Sydney have used human stem cells to make pain-killing neurons that provide lasting relief in mice, without side effects, in a single treatment.

A breakthrough gene therapy treatment for Haemophilia A has been shown to offer long-term benefits that have already transformed the lives of 13 men in the UK.

For the first time, artificial embryos made without sperm or eggs have started to form live fetuses after being implanted in female mice.

Researchers at Qatar University, in collaboration with Imperial College London, Biostage, Inc. in the U.S., and the American University of Beirut, Lebanon, have made progress developing living heart valves that can grow with the body and integrate with the patients native tissue.

ISSCR has become aware of recent claims that stem cells can be used to treat people infected with COVID-19. While stem cell research shows promise for numerous diseases and conditions, there currently are no approved stem cell-based approaches for the prevention and treatment of COVID-19 infection.