£26 million for spin-out developing advanced liver damage cell therapy
Resolution Therapeutics Ltd, a spin-out from the Centre for Regenerative Medicine (both Edinburgh, UK), has secured £26 million to further their research into a macrophage-based cell therapy targeting liver cirrhosis.
Expanding the toolbox for transcription factor-mediated iPSC differentiation
Scientists at the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden (Dresden, Germany), Harvard University (MA, USA) and the University of Bonn (Bonn, Germany) have developed a method to extract hundreds of different cells from induced pluripotent stem cells (iPSCs) using transcription factors.
CRISPR Technologies for the New Era of Cell and Gene Therapy
Experts will discuss how they use new CRISPR technologies to advance their cell and gene therapy research.
New CAR-T therapy shows promise against neuroblastoma
A novel CAR-T therapy has been developed by researchers at University College London (UK), with the purpose of targeting cancerous tumors. The investigators noted that the therapy has shown promising early results in children with neuroblastoma.
Mini kidneys developed using cutting-edge technology involving stem cells
New cutting-edge technology has been used to bioprint miniature human kidneys in the lab. The team, which comprises of researchers from the Murdoch Children’s Research Institute (Parkville, Australia) and Organovo (CA, USA), hope that these mini kidneys can be used for the treatment of kidney failure and possibly lab-grown transplant tissues.
Clinical Trial to Test CRISPR-modified T-cells in Treating Advanced Cancers
Immune cells that have been genetically engineered using CRISPR technology will be tested for a first time as a potential treatment of metastatic gastrointestinal cancer in a clinical trial.
New therapy to target the spread of bowel cancer
For the first time, SAHMRI and University of Adelaide researchers are investigating gene therapy as an option to help people with metastatic bowel cancer.
Scientists develop new gene therapy for eye disease
Scientists from Trinity College Dublin have developed a new gene therapy approach that offers promise for one day treating an eye disease that leads to a progressive loss of vision and affects thousands of people across the globe.
Investigational New Drug (IND) Update
In this first IND update from CRISPR Medicine News, we look at three pre-clinical-stage CRISPR-engineered cell therapies that are under development for the treatment of sickle cell disease (SCD), beta-thalassemia, or acute lymphoblastic leukaemia (ALL).
