Human adipose-derived mesenchymal stem cells utilized to treat cartilage defects in Phase IIa trial
In this research article, human adipose-derived mesenchymal progenitor cells were investigated both for safety and efficacy in treating cartilage defects in 30 patients.
New regeneration method to repair severely damaged lungs
New research has described a model capable of regenerating severely damaged lungs to meet criteria for transplantation. This development has the potential to increase the number of lungs available for transplant.
New liver cell may cure liver disease without transplants
Novel research, employing single-cell RNA sequencing, has characterized a new liver cell population that may be capable of liver tissue regeneration.
Phase II trial shows new CAR-T therapy is viable in acute lymphoblastic leukemia patients
In a new Phase II ‘ZUMA-3’ study from researchers at Kite, a Gilead Company (CA, USA), a novel chimeric antigen receptor (CAR) T-cell therapy known as Tecartus has been evaluated in patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL), which is an aggressive form of blood cancer.
Reprogramming skin cells into eye cells restored sight
Researchers have restored sight to blind mice by reprogramming skin cells into eye cells.
Jellyfish collagen-based cell culture reduces contamination risk and inconsistency
A novel jellyfish-based hydrogel could enable contaminant-free cell culture with higher consistency and biocompatibility, and lower risk of off-target effects.
The Cell and Gene Therapy Catapult: consortium formed for improvement of manufacturing processes
The Cell and Gene Therapy Catapult (London, UK), with the support of Innovate UK (Swindon, UK), have formed a consortium of over 20 organizations to advance technology development in the fields of cell and gene therapy.
