Stem cell enlargement contributes to decline in normal function during aging
Cells of the same type are strikingly uniform in size, while cell size differs between different cell types. This raises the question of whether cell size is important for cellular physiology.
Diabetes reverted in mice with CRISPR—Cas9 gene-edited cells from patients
iPSCs from a patient with Wolfram syndrome were programmed into insulin-producing cells, which alleviated diabetes when transplanted into mice.
Skeletal stem cell fate is decided by fatty acids and blood
Skeletal stem cells can be influenced by nutrient levels in the blood to form either bone or cartilage after bone damage.