Regenerative Medicine and Stem Cells Technologies

Analysis of male- and female-derived tumor samples revealed differences in prognostic biomarkers, genes that drive cancer, and in regulation of key pathways that may predict responses to treatment, according to results published in two studies in Cancer Research, a journal of the American Association for Cancer Research.

T cells are cells of the immune system that fight infections, but also have the potential to eliminate cancer cells. Los Angeles: Scientists have developed a new technique to turn pluripotent stem cells which can give rise to every cell type in the body into mature T cells capable of killing tumours. The technique developed by researchers at the University of California, Los Angeles (UCLA) in the US uses structures called artificial thymic organoids, which work by mimicking the environment of the thymus, the organ in which T cells develop from blood stem cells.

Researchers have developed a three-dimensional organ on a chip which enables real-time continuous monitoring of cells, and could be used to develop new treatments for disease while reducing the number of animals used in research.

Nonmyeloablative hematopoietic stem cell transplantation (HSCT) was associated with prolonged time to disease progression when compared to disease-modifying therapies (DMT) for patients with relapsing-remitting multiple sclerosis (RRMS), according to results published in Journal of the American Medical Association (JAMA).

The scientific secretary of “symposium on use of stem cells in treatment of neonatal diseases” regarded the objective of the event to be evaluating the practical approaches in implementation, presenting new services in this field, and designing and performing applied research to provide services to relevant groups.

On the 24th Razi Research Festival on Medical Sciences, the vice president for science and technology affairs expressed: in Iran, there is no more money-making area in the field of science and technology than medicine. By investing in this area, capital and value added can be multiplied.

McMaster University researchers have provided evidence of new cancerous cells they have termed cancer regenerating cells, which are responsible for the return of acute myeloid leukemia after remission.

Immune cells called macrophages are supposed to serve and protect, but cancer has found ways to put them to sleep. Now researchers at the Abramson Cancer Center of the University of Pennsylvania say theyve identified how to fuel macrophages with the energy needed to attack and eat cancer cells.

The team grew beta cells from human stem cells, but they made numerous changes to the "recipe" for producing insulin-producing beta cells.

A large, multi-center study refutes earlier suggestions that antiviral drugs for treating hepatitis C may lead to a higher recurrence of liver cancer.