New hope for treating diabetic wounds that just wont heal
One of the most frustrating and debilitating complications of diabetes is the development of wounds on the foot or lower leg. Once they form, they can persist for months, leading to painful and dangerous infections.
Next-Generation CAR-T Company Raises €130M on NASDAQ IPO
Founded in 2014 as a spin-out from University College London, Autolus has been taking great strides to develop its CAR-T technology. In less than four years, the company managed to raise nearly €150M in three funding rounds.
Artificial muscles promise to speed up testing of treatments for muscle diseases
Artificial muscles grown from human stem cells could pave the way forward for treating muscle diseases, according to new research led by UCL.
CRISPR technology may improve accuracy of predicting heart disease risk
Scientists may now be able to predict whether carrying a specific genetic variant increases a person’s risk for disease using gene editing and stem cell technologies.
New light shed on how bone marrow niches keep stem cells thriving
Hematopoietic stem cells (HSCs) are a class of stem cells located in bone marrow. HSCs give rise to every type of blood cell from the red blood cells that carry oxygen to the white blood cells of the immune system.
Scientists develop a new model for glioblastoma using gene-edited organoids
Glioblastoma multiforme (GBM) is an incredibly deadly brain cancer and presents a serious black box challenge. Its virtually impossible to observe how these tumors operate in their natural environment and animal models dont always provide good answers.
Researchers succeed in cultivating cartilage from stem cells
Researchers have produced stable joint cartilage from adult stem cells originating from bone marrow. This was made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
New CD22 CAR-T cell therapy gives hope for acute lymphoblastic leukemia
A new clinical study has shown that CD22 CAR-T cell therapy is a highly effective and safe treatment option for children with B acute lymphoblastic leukemia.
Clinical Trial of Potential CAR T-cell Therapy for Advanced Multiple Myeloma to Open in US
Janssen recently initiated a Phase 1b/2 clinical development program to evaluate JNJ-68284528, a chimeric antigen receptor (CAR) T-cell therapy, as a possible treatment of relapsed or refractory multiple myeloma.
Harnessing ‘rogue’ stem cells to grow healthy fat could help treat metabolic disorders
One theory of obesity suggests that when the body loses the ability to make healthy brown fat, unhealthy white fat cells expand and build up around the body, leading to heart disease and other adverse effects of being overweight.
