Results of breakthrough trial for cell-based stroke therapy revealed
In a Stem Cells publication, researchers from the University of Texas Health Science Center at Houston (UTHealth; TX, USA) detail the results of a landmark Phase I clinical trial investigating the use of autologous, bone marrow-derived cells in the treatment of ischemic stroke.
In a Stem Cells publication, researchers from the University of Texas Health Science Center at Houston (UTHealth; TX, USA) detail the results of a landmark Phase I clinical trial investigating the use of autologous, bone marrow-derived cells in the treatment of ischemic stroke. The team employed serial diffusion tensor imaging to capture, for the first time, the repair of motor nerve tracts extending from the brain through the spinal cord in recovering stroke patients, demonstrating the safety and feasibility of the cell-based stroke therapy.
Lead study researcher Sean I. Savitz, Director of the Institute for Stroke and Cerebrovascular Disease (TX, USA) and a neurology professor at the McGovern Medical School at UTHealth, commented: “According to our findings, it is feasible to perform a bone marrow harvest and then infuse the cells in a wide range of stroke patients. Well-designed randomized clinical trials are needed to further assess safety and efficacy of this novel approach to enhance stroke recovery.”
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