Researchers at the University of Houston are reporting a first-of-its-kind technology that repairs heart muscle cells in mice and regenerates them following a heart attack.
The groundbreaking finding has the potential to become a powerful clinical strategy for treating heart disease in humans. Researchers used synthetic messenger ribonucleic acid (mRNA) to deliver mutated transcription factors to mouse hearts. The findings are especially important because less than 1% of adult cardiac muscle cells can regenerate, and most people die with most of the cardiomyocytes they had in their first month of life.
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