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ستاد فرهنگسازی اقتصاد دانش بنیان Gene therapy dampens epileptic seizures in early tests

Gene therapy dampens epileptic seizures in early tests

Researchers have recently developed a new gene therapy technique stemming epileptic seizures at their source. The collaboration between Charité - Universitätsmedizin Berlin (Germany) and the Medical University of Innsbruck (Austria) has demonstrated promising outcomes in animal models and human tissues, utilizing a virus to target specific regions of the brain and dampen the activity which would lead to seizures before they can begin.

ستاد فرهنگسازی اقتصاد دانش بنیان Brain stem cells have a good memory

Brain stem cells have a good memory

The cerebral cortex acts as the control centre of our cognitive processes. During embryogenesis, dozens of types of neurons with distinct functions come together to form the circuits that drive our thoughts and actions. These neurons are generated by progenitor cells, which produce them one after the other in a very precise order.

ستاد فرهنگسازی اقتصاد دانش بنیان Addition of growth factors to unique system helps new bone formation

Addition of growth factors to unique system helps new bone formation

The development of new bone can be a multistep process: first, stem cells differentiate into cartilage cells. Next, the cartilage cells become bone cells. But thats not all: the cells must experience some mechanical stresses during the transformation in order to transform efficiently from stem cells to bone cells.

ستاد فرهنگسازی اقتصاد دانش بنیان Incubation with extracellular vesicles boosts cells’ grafting ability

Incubation with extracellular vesicles boosts cells’ grafting ability

A study released in STEM CELLS demonstrates how extracellular vesicles derived from human mesenchymal stem cells (MSC-EV) are able to incorporate into human CD34+ cells, modifying their gene expression and increasing their viability and cloning ability. In a test on mice, MSC-EVs also increased the cells’ ability to lodge into bone marrow.

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