Treatment for Complex Regional Pain Syndrome
Cleveland Clinic was awarded $5.5 million from the National Institutes of Health to develop a stem cell treatment for complex regional pain syndrome, a disease that causes debilitating chronic pain.
The research shows long-term potential for providing patients suffering from chronic pain an alternative to addictive treatments like opioids.
This is the first federally-funded project to develop a therapy using human mesenchymal stem cells (hMSC) in pain management and the largest grant to investigate complex regional pain syndrome. The disease often follows a localized injury, typically an arm or leg, and leads to debilitating chronic pain, swelling, color change and unbearable sensitivity to touch. The symptoms can be so severe that getting dressed or laying down to sleep can be difficult and painful.
Experts believe complex regional pain syndrome results from dysregulating neuroimmune pathways that regulate pain. Painkillers, antidepressants, nerve blocks and lifestyle changes typically have limited effects in managing symptoms, but delivering hMSC could potentially regulate the disease processes causing the chronic pain.
ارسال به دوستان