Pioneering Stem Cell Therapy Offers New Hope for Epilepsy Treatment
In what could lead to a revolutionary advancement in the treatment of temporal lobe epilepsy, UC San Diego Health has become one of the first health systems in the country to inject regenerative cells into the brain to treat epileptic seizures.
Researchers embarked on a groundbreaking clinical trial involving the injection of regenerative cells into the brain to treat epileptic seizures.
This experimental therapy, called NRTX-1001, has the potential to offer drug-resistant temporal lobe epilepsy patients a non-destructive cure for their seizures. The injected cells, derived from human stem cells, are aimed at restoring brain balance and calming seizures.
Early results show a more than 90% reduction in seizure frequency in initial patients post-treatment.
The clinical trial, sponsored by Neurona Therapeutics, is seeking to enroll 40 participants across the country to study the results of the implantation of the stem cells, which produce gamma-aminobutyric acid (GABA) — a neurotransmitter that blocks overactive impulses between nerve cells in the brain.
Shih, the principal investigator for UC San Diego Health’s involvement, said the study is the most complex clinical trial he’s served on in his career, spanning 25 years of conducting clinical trials at three leading academic institutions across the country.
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