Dr. Thomas Rando, director of the UCLA Broad Stem Cell Research Center and head of the study, said the research aimed to investigate how stem cells – which have the ability to develop into different types of cells in the body – can be better utilized to reduce the effects of aging, including chronic inflammation, cardiovascular diseases and cancer.
The study found that regular exercise reduced inflammation in mice, specifically in groups of stem cells in the blood, brain and muscle. In particular, older mice experienced inflammation reduction in skeletal muscle and restoration of communication between cells, the latter of which is vital for cell development and function.
William Lowry, associate director of education and technology transfer at the UCLA Broad Stem Cell Research Center, said “If you can wake up stem cells during aging, maybe you can prevent the onset of aging,”.
Lowry, whose own research focuses on how hair follicle stem cells can serve as a model for developmental disorders and cancer, added that stem cell research is still a growing field with much potential because of the many different applications of stem cells in the human body and scientific research.
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