Researchers from the Singapore University of Technology and Design (SUTD) have 3D-printed micro-scaled devices to enhance the production of cardiomyocytes from stem cells. The study, published in Bioprinting, demonstrates the ability of these devices to control various parameters such as cell numbers, size and sphericity of embryoid bodies that drive the differentiation of stem cells.

This novel approach is considered to be a step forward in establishing the ability to reproduce the complexity of living organisms, where several cell types coexist and collaborate to form an organ.

Javier Fernandez (SUTD), principle investigator of the study, commented: “The field of additive manufacturing is evolving at an unrivaled pace. We are seeing levels of precision, speed and cost that were inconceivable just a few years ago. What we have demonstrated is that 3D printing has now reached the point of geometrical accuracy where it is able to control the outcome of stem cell differentiation. And in doing so, we are propelling regenerative medicine to further advance alongside the accelerated rate of the additive manufacturing industry.”

Link: https://www.regmednet.com/3d-printed-device-developed-for-directed-stem-cell-differentiation/