Doctor Clare Slaney and her team are exploring using COVID-19 immunity to treat breast cancer.
They are working on ways to improve chimeric antigen receptor (CAR) T therapy, a type of immunotherapy, with funding support from the National Breast Cancer Foundation.
While CAR T therapy has shown great promise in some blood cancers, to date, it has not proved to be as effective for solid tumors like breast cancer. The opportunity that this research presents is identifying a mechanism capable of generating CAR T cells using COVID-19 viral specific T cells that already exist in most people after the pandemic.
Dr Slaney and her team from Peter Mac/University of Melbourne will collect COVID-19 memory T cells from people who have been infected and/or been vaccinated against COVID-19. By re-engineering these cells to recognize specific breast cancer surface proteins, these T cells could be used to fight breast cancers.
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